Salt: A Caution

The following is a summary by Dragon Claw

Interleukin (IL) 17–producing helper cells are a key component in the induction of multiple autoimmune diseases.

A new study finds that serum glucocorticoid kinase I (SGK1) plays a critical role in this process. SGK1, an enzyme located primarily in the gut and kidney, regulates sodium absorption and sodium balance.

Chuan Wu, PhD of Harvard Medical School in Boston, found that if they increased salt, they were able to induce SGK1 and increase the number of IL17 cells.  They also found that mice that were placed on a high salt diet became more susceptible to an autoimmune model of multiple sclerosis. 

The results suggest that a high salt diet may be a risk factor for inflammation.

Source:  Salt as a Promoter of Th17 Cells and Autoimmune Disease; May 21, 2013 By Lara C. Pullen, PhD in The Rheumatologist.

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